Zepbound®
The same tirzepatide in a prefilled single-dose pen — no needle handling or priming.
Learn MoreTirzepatide injection · multi-dose KwikPen® · by Eli Lilly
Zepbound® KwikPen® delivers four once-weekly tirzepatide doses in a single device — with a licensed provider guiding your plan from day one.
Prescription only. A licensed clinician determines whether treatment is appropriate. Always read and follow the Instructions for Use supplied with your KwikPen.

One pen. Four weekly doses.
Brand-name Zepbound® KwikPen®, prescribed online and shipped to your door through licensed pharmacy partners.
Mechanism
Tirzepatide targets GIP and GLP-1 receptors to help curb hunger and support weight loss.

The KwikPen® delivers tirzepatide under the skin — one dose each week, four doses per pen.
Two incretin pathways involved in appetite, fullness, and how the body handles food.
Digestion slows and hunger signals quiet, so smaller portions feel natural.
Alongside a reduced-calorie eating pattern and increased physical activity.
Clinical evidence
20.9% average body-weight reduction at 15 mg in a 72-week trial (average starting weight about 231 lb), versus 3.1% with placebo. Individual results vary, and your provider chooses your dose based on response and tolerability.
15 mg maintenance dose
20.9%
average body-weight loss at 72 weeks (SURMOUNT-1 trial).*
Placebo
3.1%
average body-weight loss at 72 weeks in the same trial.*

*Average 20.9% body weight loss at 72 weeks on the 15 mg dose, versus 3.1% for placebo, based on the SURMOUNT-1 clinical trial in adults with obesity or overweight plus a weight-related condition, alongside a reduced-calorie diet and increased physical activity. Individual results vary; no specific outcome is guaranteed.
Zepbound® starts low and steps up no faster than every four weeks. Each KwikPen® is labeled for one dose strength — your provider prescribes the next strength when it's time to step up.
Starting
2.5 mg
weekly
Step 1
5 mg
weekly
Step 2
7.5 mg
weekly
Step 3
10 mg
weekly
Step 4
12.5 mg
weekly
Maximum
15 mg
weekly
Maintenance doses of 5 mg, 10 mg, or 15 mg are common. Not every patient needs the highest dose.
Using your KwikPen®
A six-stage routine, once a week. Your provider walks you through the first injection, and the Instructions for Use stay with your pen.

Step 1
Wash your hands, check the label and expiration date, and confirm the medicine is clear and colorless to slightly yellow.
Step 2
Pull off the pen cap, wipe the rubber seal, and screw a new pen needle straight on. Remove both needle shields.
Step 3
Turn the dose knob to the prime symbol, hold the pen with the needle up, and press the dose button until you see medicine at the tip.
Step 4
Stomach (at least 2 inches from the navel), thigh, or back of the upper arm. Rotate sites each week.
Step 5
Dial to 1 for a full dose. Insert the needle, press and hold the dose button, and count slowly to 5 after the dial returns to 0.
Step 6
Remove and discard the needle in a sharps container. Recap the pen and store it in the refrigerator between doses.
Four device rules
Same tirzepatide, same weekly schedule, same clinical evidence. The only difference is the device.

| KwikPen® | Single-dose pen | |
|---|---|---|
| Active ingredient | Tirzepatide | Tirzepatide |
| Doses per device | 4 weekly doses | 1 dose |
| Pen needles | Attach a new needle each week | Built in, hidden |
| Priming | Required before each dose | Not required |
| Storage after first use | Refrigerate; discard after 30 days or 4 doses | Single use |
| Dose strengths | 2.5–15 mg | 2.5–15 mg |
Prefer a device with no needle handling? Learn about the single-dose Zepbound® pen.
The process
Personalized care, every step of the way.
1.
Share your health history and goals from the comfort of home — about 10 minutes.
2.
A licensed provider reviews your information and creates a plan that's right for you.
3.
Your total cost is confirmed before you commit — no insurance, no surprise bills.
4.
Brand-name Zepbound® KwikPen® ships discreetly through licensed pharmacy partners.
5.
Dose adjustments, check-ins, and real people who care.

Severe gastrointestinal reactions
Nausea, vomiting, and diarrhea can be severe, especially during dose increases. Tell your provider if symptoms don't ease.
Acute kidney injury
Vomiting or diarrhea can cause dehydration and worsen kidney function; stay hydrated.
Gallbladder disease
Gallstones and gallbladder inflammation have been reported; watch for upper-abdominal pain, fever, or yellowing of the skin.
Pancreatitis
Stop use and seek care for severe, persistent abdominal pain, with or without vomiting, that may radiate to the back.
Hypoglycemia
Risk is higher when used with insulin or sulfonylureas; know the signs of low blood sugar.
Severe allergic reactions
Stop use and get emergency help for swelling, trouble breathing, rapid heartbeat, or severe rash.
Pregnancy & medication interactions
Do not use if pregnant or planning pregnancy. Tirzepatide may reduce the effectiveness of oral contraceptives around dose increases — talk to your provider. Also report depression or suicidal thoughts and every medication you take.
Common side effects
Nausea, diarrhea, vomiting, constipation, abdominal pain, indigestion, injection-site reactions, fatigue, and decreased appetite.
Your provider reviews your BMI and weight-related conditions, personal and family thyroid history, pancreatitis and gallbladder history, kidney function, current medications, pregnancy plans, and walks you through the KwikPen® Instructions for Use.

The same tirzepatide in a prefilled single-dose pen — no needle handling or priming.
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Learn MoreTake a private assessment and a licensed provider will tell you whether Zepbound® KwikPen® — or another option — fits your history, routine, and goals.
Prescription required. Zepbound® and KwikPen® are registered trademarks of Eli Lilly and Company; Wegovy® is a registered trademark of Novo Nordisk A/S. Graceland Wellness is not affiliated with either manufacturer. Transparent self-pay pricing; medication ships directly to your door.